Media Contact:
Katrina Norfleet
Posted: 5/16/2016

Supplement mimics neuroprotective effects of low-calorie diet

Seattle, Wash. – According to new research, injection of 3-hydroxybutyrate (3HB) offers similar protection as a low calorie diet against nerve degeneration in rats with glaucoma. The research is being presented at the 2016 Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO) this week in Seattle, Wash. 

Rats were divided into three groups: low calorie, injection with 3HB and a control group. Neurodegeneration was found to be significantly higher in the control group than the low calorie and 3HB groups.

Glaucoma is a neurodegenerative disease that can result in blindness. 3HB is believed to interact with the pentose phosphate pathway.

Abstract Title: Calorie restriction protects against retinal degeneration in acute glaucoma model through altering the metabolic profile
Presentation Start/End Time: Monday, May 2, 2016, 3:45pm – 5:30pm
Location: Exhibit/Poster Hall
Abstract Number: 2564 - B0180

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The Association for Research in Vision and Ophthalmology (ARVO) is the largest eye and vision research organization in the world. Members include nearly 12,000 eye and vision researchers from over 75 countries. ARVO advances research worldwide into understanding the visual system and preventing, treating and curing its disorders. 

All abstracts accepted for presentation at the ARVO Annual Meeting represent previously unpublished data and conclusions. This research may be proprietary or may have been submitted for journal publication. Embargo policy: Journalists must seek approval from the presenter(s) before reporting data from paper or poster presentations. Press releases or stories on information presented at the ARVO Annual Meeting may not be released or published until the conclusion of the presentation.

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